Rapid fabrication of pressure - driven open - channel microfluidic devices in omniphobic RF paper 3

This paper describes the fabrication of pressure-driven, open-channel microfluidic systems with lateral dimensions of 45–300 microns carved in omniphobic paper using a craft-cutting tool. Vapor phase silanization with a fluorinated alkyltrichlorosilane renders paper omniphobic, but preserves its high gas permeability and mechanical properties. When sealed with tape, the carved channels form conduits capable of guiding liquid transport in the low-Reynolds number regime (i.e. laminar flow). These devices are compatible with complex fluids such as droplets of water in oil. The combination of omniphobic paper and a craft cutter enables the development of new types of valves and switches, such as ‘‘fold valves’’ and ‘‘porous switches,’’ which provide new methods to control fluid flow.